Neuropathology and cognitive performance in self-reported cognitively healthy centenarians

Abstract With aging, the incidence of neuropathological hallmarks of neurodegenerative diseases increases in the brains of cognitively healthy individuals. It is currently unclear to what extent these hallmarks associate with symptoms of disease at extreme ages. Forty centenarians from the 100-plus...

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Bibliographic Details

Published in:	Acta Neuropathologica Communications
Main Authors:	Andrea B. Ganz, Nina Beker, Marc Hulsman, Sietske Sikkes, Netherlands Brain Bank, Philip Scheltens, August B. Smit, Annemieke J. M. Rozemuller, Jeroen J. M. Hoozemans, Henne Holstege
Format:	Article
Language:	English
Published:	BMC 2018-07-01
Subjects:	Healthy aging Cognitively healthy centenarians 100-plus Study Neuropathology Alzheimer’s disease Clinicopathological correlation
Online Access:	http://link.springer.com/article/10.1186/s40478-018-0558-5