Epigenetic Modifications of MiRNAs in Osteoarthritis: A Systematic Review on Their Methylation Levels and Effects on Chondrocytes, Extracellular Matrix and Joint Inflammation

Osteoarthritis (OA) is a joint disorder characterized by progressive degeneration of cartilage extracellular matrix (ECM), chondrocyte hypertrophy and apoptosis and inflammation. The current treatments mainly concern pain control and reduction of inflammation, but no therapeutic strategy has been id...

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Bibliographic Details
Published in:Cells
Main Authors: Francesca Veronesi, Viviana Costa, Daniele Bellavia, Valentina Basoli, Gianluca Giavaresi
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Subjects:
osteoarthritis
miRNA methylation
cartilage epigenetic modifications
Online Access:https://www.mdpi.com/2073-4409/12/14/1821

Internet

https://www.mdpi.com/2073-4409/12/14/1821

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