Synthetic Gene Circuit-Based Assay with Multilevel Switch Enables Background-Free and Absolute Quantification of Circulating Tumor DNA

Circulating tumor DNA (ctDNA) detection has found widespread applications in tumor diagnostics and treatment, where the key is to obtain accurate quantification of ctDNA. However, this remains challenging due to the issue of background noise associated with existing assays. In this work, we develope...

詳細記述

書誌詳細

出版年:	Research
主要な著者:	Chao Zhang, Zedong Li, Jie Liu, Chang Liu, Haoqing Zhang, Won Gu Lee, Chunyan Yao, Hui Guo, Feng Xu
フォーマット:	論文
言語:	英語
出版事項:	American Association for the Advancement of Science (AAAS) 2023-01-01
オンライン･アクセス:	https://spj.science.org/doi/10.34133/research.0217