Mining and analysis of adverse event signals of isotretinoin based on the real-world data of FAERS database

ObjectiveIsotretinoin (ISO) is an oral prescription retinoid that is well-known for its effectiveness in treating acne. This study aims to provide valuable insights into the safety of its clinical use by analyzing adverse events (AEs) associated with ISO reported in the FDA Adverse Event Reporting S...

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Bibliographic Details

Published in:	Frontiers in Medicine
Main Authors:	Liu Yang, Hanzhang Xie, Ying Jia, Bingnan Cui, Zhanshuo Xiao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-10-01
Subjects:	isotretinoin pharmacovigilance FAERS database adverse events signal detection pharmacovigilance methodology
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1559972/full