Evaluating Nanoparticulate Vaccine Formulations for Effective Antigen Presentation and T-Cell Proliferation Using an In Vitro Overlay Assay

Inducing T lymphocyte (T-cell) activation and proliferation with specificity against a pathogen is crucial in vaccine formulation. Assessing vaccine candidates’ ability to induce T-cell proliferation helps optimize formulation for its safety, immunogenicity, and efficacy. Our in-house vaccine candid...

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發表在:	Vaccines
Main Authors:	Dedeepya Pasupuleti, Priyal Bagwe, Amarae Ferguson, Mohammad N. Uddin, Martin J. D’Souza, Susu M. Zughaier
格式:	Article
語言:	英语
出版:	MDPI AG 2024-09-01
主題:	T-cell proliferation overlay assay cell-to-cell contact antigen-presenting cell dendritic cell antigen presentation
在線閱讀:	https://www.mdpi.com/2076-393X/12/9/1049