Learning functional conservation between human and pig to decipher evolutionary mechanisms underlying gene expression and complex traits

Summary: Assessment of genomic conservation between humans and pigs at the functional level can improve the potential of pigs as a human biomedical model. To address this, we developed a deep learning-based approach to learn the genomic conservation at the functional level (DeepGCF) between species...

Full description

Bibliographic Details

Published in:	Cell Genomics
Main Authors:	Jinghui Li, Tianjing Zhao, Dailu Guan, Zhangyuan Pan, Zhonghao Bai, Jinyan Teng, Zhe Zhang, Zhili Zheng, Jian Zeng, Huaijun Zhou, Lingzhao Fang, Hao Cheng
Format:	Article
Language:	English
Published:	Elsevier 2023-10-01
Subjects:	deep learning functional conservation human pig complex trait gene expression
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666979X23001878