Larazotide Acetate Protects the Intestinal Mucosal Barrier from Anoxia/Reoxygenation Injury via Various Cellular Mechanisms

<b>Background/Objective</b>: Larazotide acetate (LA) is a synthetic octapeptide under development as a therapeutic candidate for celiac disease, acting to reduce intestinal permeability and regulate tight junctions (TJs). Although several studies have shown barrier-protective effects, th...

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Bibliographic Details
Published in:Biomedicines
Main Authors: Jain Kim, Jay P. Madan, Sandeep Laumas, B. Radha Krishnan, Younggeon Jin
Format: Article
Language:English
Published: MDPI AG 2025-10-01
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Online Access:https://www.mdpi.com/2227-9059/13/10/2483