Cytotoxic action of maleimide derivative 1-(4-Cl-benzyl)-3-chloro-4-(CF(3)-phenylamino)-1H-pyrrole-2,5-dione toward mammalian tumor cells and its capability to interact with DNA

Development of chemical compounds capable to supress tumor progression is a perspective strategy of cancer treatment. Heterocyclic compounds possess a broad spectrum of biological activities, including anticancer one. According to the previous results of in silico modeling maleimide derivative 1-(4-...

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الحاوية / القاعدة:	The Ukrainian Biochemical Journal
المؤلفون الرئيسيون:	N. S. Finiuk, I. I. Ivasechko, O. Yu. Klyuchivska, H. M. Kuznietsova, V. K. Rybalchenko, R. S. Stoika
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	National Academy of Sciences of Ukraine, Palladin Institute of Biochemistry 2020-08-01
الموضوعات:	1-(4-cl-benzil)-3-cl-4-(cf3-phenylamino)-1н-pyrrole-2.5-dione anticancer activity мтт
الوصول للمادة أونلاين:	http://ukrbiochemjournal.org/wp-content/uploads/2020/09/Finiuk_4_20.pdf