Transcriptome- and proteome-wide association studies nominate determinants of kidney function and damage

Abstract Background The pathophysiological causes of kidney disease are not fully understood. Here we show that the integration of genome-wide genetic, transcriptomic, and proteomic association studies can nominate causal determinants of kidney function and damage. Results Through transcriptome-wide...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Genome Biology
المؤلفون الرئيسيون: Pascal Schlosser, Jingning Zhang, Hongbo Liu, Aditya L. Surapaneni, Eugene P. Rhee, Dan E. Arking, Bing Yu, Eric Boerwinkle, Paul A. Welling, Nilanjan Chatterjee, Katalin Susztak, Josef Coresh, Morgan E. Grams
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2023-06-01
الموضوعات:
Genetics
Nephrology
Chronic kidney disease
Transcriptomics
Proteomics
GWAS
الوصول للمادة أونلاين:https://doi.org/10.1186/s13059-023-02993-y

الانترنت

https://doi.org/10.1186/s13059-023-02993-y

مواد مشابهة