A Deep Learning Approach to Optimize Recombinant Protein Production in <i>Escherichia coli</i> Fermentations

Fermentation is a widely used process in the biotechnology industry, in which sugar-based substrates are transformed into a new product through chemical reactions carried out by microorganisms. Fermentation yields depend heavily on critical process parameter (CPP) values which need to be finely tune...

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Bibliographic Details

Published in:	Fermentation
Main Authors:	Domenico Bonanni, Mattia Litrico, Waqar Ahmed, Pietro Morerio, Tiziano Cazzorla, Elisa Spaccapaniccia, Franca Cattani, Marcello Allegretti, Andrea Rosario Beccari, Alessio Del Bue, Franck Martin
Format:	Article
Language:	English
Published:	MDPI AG 2023-05-01
Subjects:	<i>E. coli</i> neurotrophin OD<sub>600nm</sub> fermentation process optimization machine learning
Online Access:	https://www.mdpi.com/2311-5637/9/6/503