NK cells propagate T cell immunity following in situ tumor vaccination

Summary: We report an in situ vaccination, adaptable to nearly any type of cancer, that combines radiotherapy targeting one tumor and intratumoral injection of this site with tumor-specific antibody and interleukin-2 (IL-2; 3xTx). In a phase I clinical trial, administration of 3xTx (with an immunocy...

詳細記述

書誌詳細

出版年:	Cell Reports
主要な著者:	Won Jong Jin, Justin C. Jagodinsky, Jessica M. Vera, Paul A. Clark, Cindy L. Zuleger, Amy K. Erbe, Irene M. Ong, Trang Le, Kaitlin Tetreault, Tracy Berg, Alexander L. Rakhmilevich, KyungMann Kim, Michael A. Newton, Mark R. Albertini, Paul M. Sondel, Zachary S. Morris
フォーマット:	論文
言語:	英語
出版事項:	Elsevier 2023-12-01
主題:	CP: Cancer CP: Immunology
オンライン･アクセス:	http://www.sciencedirect.com/science/article/pii/S2211124723015681