Evasion by stealth: inefficient immune activation underlies poor T cell response and severe disease in SARS-CoV-infected mice.

Severe Acute Respiratory Syndrome caused substantial morbidity and mortality during the 2002-2003 epidemic. Many of the features of the human disease are duplicated in BALB/c mice infected with a mouse-adapted version of the virus (MA15), which develop respiratory disease with high morbidity and mor...

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Bibliographic Details
Published in:PLoS Pathogens
Main Authors: Jincun Zhao, Jingxian Zhao, Nico Van Rooijen, Stanley Perlman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-10-01
Online Access:http://europepmc.org/articles/PMC2762542?pdf=render