IDO and Kynurenine Metabolites in Peripheral and CNS Disorders

The importance of the kynurenine pathway in normal immune system function has led to an appreciation of its possible contribution to autoimmune disorders such as rheumatoid arthritis. Indoleamine-2,3-dioxygenase (IDO) activity exerts a protective function, limiting the severity of experimental arthr...

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Bibliographic Details
Published in:Frontiers in Immunology
Main Authors: Yi-Shu Huang, Joy Ogbechi, Felix I. Clanchy, Richard O. Williams, Trevor W. Stone
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Subjects:
kynurenine
arthritis
lymphocyte antigens
3-hydroxyanthranilic acid
Huntington's disease
T-cells
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00388/full

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https://www.frontiersin.org/article/10.3389/fimmu.2020.00388/full

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