Multifaceted neuroprotective approach of Trolox in Alzheimer's disease mouse model: targeting Aβ pathology, neuroinflammation, oxidative stress, and synaptic dysfunction

Alzheimer's disease (AD) is a progressive neurodegenerative disorder pathologically characterized by the deposition of amyloid beta (Aβ) plaques and neurofibrillary tangles (NFTs) in the brain. The accumulation of these aggregated proteins causes memory and synaptic dysfunction, neuroinflammati...

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Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Muhammad Tahir, Min Hwa Kang, Tae Ju Park, Jawad Ali, Kyonghwan Choe, Jun Sung Park, Myeong Ok Kim
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-09-01
Subjects:	Alzheimer's disease (AD) amyloid beta plaques (Aβ) neurofibrillary tangles (NFTs) Trolox neuroinflammation oxidative stress and neurodegeneration
Online Access:	https://www.frontiersin.org/articles/10.3389/fncel.2024.1453038/full