CD6 regulates CD4 T follicular helper cell differentiation and humoral immunity during murine coronavirus infection

ABSTRACT During activation, the T cell transmembrane receptor CD6 becomes incorporated into the T cell immunological synapse where it can exert both co-stimulatory and co-inhibitory functions. Given the ability of CD6 to carry out opposing functions, this study sought to determine how CD6 regulates...

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Bibliographic Details
Published in:Journal of Virology
Main Authors: Amber Cardani-Boulton, Feng Lin, Cornelia C. Bergmann
Format: Article
Language:English
Published: American Society for Microbiology 2025-01-01
Subjects:
CD6
antiviral immunity
T follicular helper cells
germinal centers
humoral immunity
MHV
Online Access:https://journals.asm.org/doi/10.1128/jvi.01864-24

Internet

https://journals.asm.org/doi/10.1128/jvi.01864-24

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