Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity

Abstract Mitochondrial dynamics enable cellular adaptation to fluctuations in energy demand, such as those imposed on skeletal muscle by exercise, metabolic disorders, or aging. Here, we report a novel pathway that modulates mitochondria dynamics in skeletal muscle involving the scaffolding protein...

Full description

Bibliographic Details

Published in:	Nature Communications
Main Authors:	Kayleigh M. Voos, Joyce Tzeng, Priya Patel, Sophie Rubinsky, Ha E. Choi, Trevor Pharr, Sebastian Sookram, Joseph A. Baur, Erik J. Soderblom, Damaris N. Lorenzo
Format:	Article
Language:	English
Published:	Nature Portfolio 2025-08-01
Online Access:	https://doi.org/10.1038/s41467-025-62977-3