Toxicity of immune checkpoint inhibitors and tyrosine kinase inhibitor combinations in solid tumours: a systematic review and meta-analysis

The combination of immune checkpoint inhibitors (ICIs) and tyrosine kinase inhibitors (TKIs) can be associated with significant toxicity. We performed a systematic review and meta-analysis of the toxicity of combination treatment of ICIs with TKIs (ICI + TKI) in clinical trials with solid organ mali...

Full description

Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	David O’Reilly, Caroline L. O’Leary, Aislinn Reilly, Min Yuen Teo, Grainne O’Kane, Lizza Hendriks, Kathleen Bennett, Jarushka Naidoo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2024-07-01
Subjects:	tyrosine kinase inhibitors immunotherapy toxicity immune related adverse events immune checkpoint blockade
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2024.1380453/full