Intron retention as a productive mechanism in human MAPT: RNA species generated by retention of intron 3Research in context

Summary: Background: Tau is a microtubule-binding protein encoded by the MAPT gene. Tau is essential for several physiological functions and associated with pathological processes, including Alzheimer's disease (AD). Six tau isoforms are typically described in the central nervous system, but c...

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الحاوية / القاعدة:	EBioMedicine
المؤلفون الرئيسيون:	Daniel Ruiz-Gabarre, Laura Vallés-Saiz, Almudena Carnero-Espejo, Isidro Ferrer, Félix Hernández, Ramon Garcia-Escudero, Jesús Ávila, Vega García-Escudero
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Elsevier 2024-02-01
الموضوعات:	Tau Alzheimer's disease Alternative splicing Intron retention Tau isoforms Tauopathies
الوصول للمادة أونلاين:	http://www.sciencedirect.com/science/article/pii/S2352396423005194