An in vitro Co-culture System for the Activation of CD40 by Membrane-presented CD40 Ligand versus Soluble Agonist

One fundamental property of the TNR receptor (TNFR) family relates to how ‘signal quality’ (the extent of receptor ligation or cross-linking) influences the outcome of receptor ligation, for instance the induction of death in tumour cells. It is unequivocal that membrane-presented ligand (delivered...

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Bibliographic Details
Published in:Bio-Protocol
Main Authors: Khalidah Ibraheem, Christopher Dunnill, Myria Ioannou, Albashir Mohamed, Balid Albarbar, Nik Georgopoulos
Format: Article
Language:English
Published: Bio-protocol LLC 2018-07-01
Online Access:https://bio-protocol.org/en/bpdetail?id=2907&type=0