A COMPUTATIONAL STUDY ON Ca²⁺ MODULATION OF ASIC 1 PHARMACOLOGIC PROPERTIES

Acid-sensing ion channel (ASIC) is involved in important processes like synaptic plasticity and learning, fear and anxiety, pain sensation. Due to its role in neurodegeneration and neuroinflammation, the channel is a viable pharmacological target. The channel is activated by acid pH pulses and it r...

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Bibliographic Details

Published in:	Studia Universitatis Babes-Bolyai Chemia
Main Authors:	Raluca NICULAE, Maria MERNEA, Loredana GHICA, Dan Florin MIHĂILESCU
Format:	Article
Language:	English
Published:	Babes-Bolyai University 2021-09-01
Subjects:	ASIC1, molecular docking, protein-ligand interaction, pharmacology.
Online Access:	https://studia.reviste.ubbcluj.ro/index.php/chemia/article/view/7846