Hyperoside mitigates amphotericin B-induced nephrotoxicity in HK-2 cells via bioenergetic and oxidative stress modulation
Abstract Amphotericin B (Amp-B/FZ), a first-line antifungal, is limited by dose-dependent nephrotoxicity. This study investigated the protective effects of hyperoside (HP), a dietary flavonoid, against FZ-induced renal toxicity in human proximal tubular (HK-2) cells. Molecular docking revealed stron...
| الحاوية / القاعدة: | BMC Pharmacology and Toxicology |
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| المؤلفون الرئيسيون: | , , , , , , , |
| التنسيق: | مقال |
| اللغة: | الإنجليزية |
| منشور في: |
BMC
2025-08-01
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://doi.org/10.1186/s40360-025-00985-1 |
