AI‐Driven De Novo Design of Ultra Long‐Acting GLP‐1 Receptor Agonists

Abstract Peptide drugs have revolutionized modern therapeutics, offering novel treatment avenues for various diseases. Nevertheless, low design efficacy, time consumption, and high cost still hinder peptide drug design and discovery. Here, an efficient approach that integrates deep learning‐based pr...

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Bibliographic Details
Published in:Advanced Science
Main Authors: Ting Wei, Jiating Ma, Xiaochen Cui, Jiahui Lin, Zhuoqi Zheng, Liu Cheng, Taiying Cui, Xiaoqian Lin, Junjie Zhu, Xuyang Ran, Xiaokun Hong, Luke Johnston, Zhangsheng Yu, Haifeng Chen
Format: Article
Language:English
Published: Wiley 2025-10-01
Subjects:
deep learning
GLP‐1RAs
protein design
Semaglutide
Online Access:https://doi.org/10.1002/advs.202507044

Internet

https://doi.org/10.1002/advs.202507044

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