Xymedon and its conjugate with <i>L</i>-ascorbic acid for treating experimentally induced liver fibrosis in rats

This study evaluates the antifibrotic properties of Xymedon, a pyrimidine derivative (1,2-dihydro-4,6-dimethyl-1-(2-hydroxyethyl)-pyrimidin-2-one), and its conjugate with L-ascorbic acid in a rat model of experimental liver fibrosis. Liver fibrosis was induced in female Wistar rats by oral administr...

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Bibliographic Details

Published in:	Учёные записки Казанского университета: Серия Естественные науки
Main Authors:	G. P. Belyaev, A. B. Vyshtakalyuk, A. A. Parfenov, I. V. Galyametdinova, V. E. Semenov, V. V. Zobov
Format:	Article
Language:	English
Published:	Kazan Federal University 2025-06-01
Subjects:	pyrimidine derivatives xymedon fibrosis inflammation cytokines cyclooxygenase-2
Online Access:	https://uzakuesc.elpub.ru/jour/article/view/347