Pioneering discovery: US3-phosphorylated sites on VP22 orchestrate duck plague virus release and pathogenicity

Duck plague virus (DPV), a member of the Alphaherpesvirinae subfamily, causes severe infectious disease in waterfowl and Anseriformes birds. Although the VP22 protein (encoded by the UL49 gene) is known to play a pivotal role in secondary viral envelopment, its post-translational modifications and r...

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Bibliographic Details

Published in:	Poultry Science
Main Authors:	Liping Wu, Anchun Cheng, Mingshu Wang, Qiao Yang, Xumin Ou, Di Sun, Yu He, Zhen Wu, Bin Tian, Juan Huang, Ying Wu, Shaqiu Zhang, Xinxin Zhao, Yanling Yu, Ling Zhang, Dekang Zhu, Mafeng Liu, Renyong Jia, Shun Chen
Format:	Article
Language:	English
Published:	Elsevier 2025-12-01
Subjects:	Duck plague virus Tegument protein VP22 US3 protein kinase Phosphorylation Pathogenesis
Online Access:	http://www.sciencedirect.com/science/article/pii/S0032579125011484