Insights on the epigenetic mechanisms underlying pulmonary arterial hypertension

Pulmonary arterial hypertension (PAH), characterized by localized increased arterial blood pressure in the lungs, is a slow developing long-term disease that can be fatal. PAH is characterized by inflammation, vascular tone imbalance, pathological pulmonary vascular remodeling, and right-sided heart...

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Bibliographic Details
Published in:Brazilian Journal of Medical and Biological Research
Main Authors: R.C.P. Luna, Y. de Oliveira, J.V.C. Lisboa, T.R. Chaves, T.A.M. de Araújo, E.E. de Sousa, M. Miranda Neto, L. Pirola, V.A. Braga, J.L. de Brito Alves
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-10-01
Subjects:
Epigenetic
Pulmonary arterial hypertension
DNA Methylation
Histone acetylation
miRNAs
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200301&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200301&lng=en&tlng=en

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