Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke

Abstract Preclinical and clinical proof-of-concept studies have suggested the effectiveness of pharmacological modulation of inflammatory cytokines in ischemic stroke. Experimental evidence shows that targeting tumor necrosis factor (TNF) and interleukin (IL)-1 holds promise, and these cytokines are...

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Bibliographic Details

Published in:	Acta Neuropathologica Communications
Main Authors:	Bettina H. Clausen, Martin Wirenfeldt, Sofie S. Høgedal, Lars H. Frich, Helle H. Nielsen, Henrik D. Schrøder, Kamilla Østergaard, Bente Finsen, Bjarne W. Kristensen, Kate L. Lambertsen
Format:	Article
Language:	English
Published:	BMC 2020-06-01
Subjects:	Apoplexy Microglia Leukocytes Cytokines
Online Access:	http://link.springer.com/article/10.1186/s40478-020-00957-y