BDNF-Live-Exon-Visualization (BLEV) Allows Differential Detection of BDNF Transcripts in vitro and in vivo

Bdnf exon-IV and exon-VI transcripts are driven by neuronal activity and are involved in pathologies related to sleep, fear or memory disorders. However, how their differential transcription translates activity changes into long-lasting network changes is elusive. Aiming to trace specifically the ne...

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Bibliographic Details

Published in:	Frontiers in Molecular Neuroscience
Main Authors:	Wibke Singer, Marie Manthey, Rama Panford-Walsh, Lucas Matt, Hyun-Soon Geisler, Eleonora Passeri, Gabriele Baj, Enrico Tongiorgi, Graciano Leal, Carlos B. Duarte, Ivan L. Salazar, Philipp Eckert, Karin Rohbock, Jing Hu, Jörg Strotmann, Peter Ruth, Ulrike Zimmermann, Lukas Rüttiger, Thomas Ott, Thomas Schimmang, Marlies Knipper
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-09-01
Subjects:	BDNF detection Bdnf exon-IV and -VI transgenic BDNF reporter mice activity-dependent BDNF expression long-lasting plasticity changes
Online Access:	https://www.frontiersin.org/article/10.3389/fnmol.2018.00325/full