Characterization of the Interaction Between SARS-CoV-2 Membrane Protein (M) and Proliferating Cell Nuclear Antigen (PCNA) as a Potential Therapeutic Target

SARS-CoV-2 is an emerging virus from the Coronaviridae family and is responsible for the ongoing COVID-19 pandemic. In this work, we explored the previously reported SARS-CoV-2 structural membrane protein (M) interaction with human Proliferating Cell Nuclear Antigen (PCNA). The M protein is responsi...

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Bibliographic Details

Published in:	Frontiers in Cellular and Infection Microbiology
Main Authors:	Érika Pereira Zambalde, Isadora Carolina Betim Pavan, Mariana Camargo Silva Mancini, Matheus Brandemarte Severino, Orlando Bonito Scudero, Ana Paula Morelli, Mariene Ribeiro Amorim, Karina Bispo-dos-Santos, Mariana Marcela Góis, Daniel A. Toledo-Teixeira, Pierina Lorencini Parise, Thais Mauad, Marisa Dolhnikoff, Paulo Hilário Nascimento Saldiva, Henrique Marques-Souza, José Luiz Proenca-Modena, Armando Morais Ventura, Fernando Moreira Simabuco
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-05-01
Subjects:	SARS-CoV-2 PCNA M protein viral-host interaction DNA damage
Online Access:	https://www.frontiersin.org/articles/10.3389/fcimb.2022.849017/full