Placental growth factor mediates pathological uterine angiogenesis by activating the NFAT5-SGK1 signaling axis in the endometrium: implications for preeclampsia development

Abstract After menstruation the uterine spiral arteries are repaired through angiogenesis. This process is tightly regulated by the paracrine communication between endometrial stromal cells (EnSCs) and endothelial cells. Any molecular aberration in these processes can lead to complications in pregna...

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Bibliographic Details

Published in:	Biological Research
Main Authors:	Janet P. Raja Xavier, Toshiyuki Okumura, Melina Apweiler, Nirzari A. Chacko, Yogesh Singh, Sara Y Brucker, Satoru Takeda, Florian Lang, Madhuri S Salker
Format:	Article
Language:	English
Published:	BMC 2024-08-01
Subjects:	PlGF Endometrium Placentation Pregnancy Preeclampsia SGK1
Online Access:	https://doi.org/10.1186/s40659-024-00526-w