Prognostic implications and characterization of tumor-associated tertiary lymphoid structures genes in pancreatic cancer

Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is among the most aggressive cancers, with rising incidence and limited responsiveness to immunotherapy due to its highly suppressive tumor microenvironment (TME). Tertiary lymphoid structures (TLS), ectopic formation structures of immune c...

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出版年:	Journal of Translational Medicine
主要な著者:	Enkui Zhang, Yongsu Ma, Zonghao Liu, Jixin Zhang, Weikang Liu, Yiran Chen, Guangnian Liu, Xinxin Liu, Fusheng Zhang, Yu Zhu, Yinmo Yang, Xiaodong Tian
フォーマット:	論文
言語:	英語
出版事項:	BMC 2025-03-01
主題:	Pancreatic cancer Tertiary lymphoid structures Tumor microenvironment Prognostic signature Characterization
オンライン･アクセス:	https://doi.org/10.1186/s12967-025-06152-8