Prophylactic Treatment with Baloxavir Protects Mice from Lethal Infection with Influenza A and B Viruses

Influenza remains a worldwide health concern. Antiviral drugs are considered as one of the useful options for its prevention as a complementary measure to vaccination. Baloxavir acid selectively inhibits the cap-dependent endonuclease of influenza viruses and exhibits marked viral titre reduction in...

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Bibliographic Details

Published in:	Viruses
Main Authors:	Keita Fukao, Takeshi Noshi, Shinya Shano, Kaoru Baba, Kenji Sato, Masashi Sakuramoto, Naohisa Kitade, Hideki Tanioka, Shinji Kusakabe, Takao Shishido
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Subjects:	influenza virus prophylaxis cap-dependent endonuclease inhibitor baloxavir marboxil baloxavir acid oseltamivir phosphate
Online Access:	https://www.mdpi.com/1999-4915/15/11/2264