Mapping of Recognition Sites of Monoclonal Antibodies Responsible for the Inhibition of Pneumolysin Functional Activity

The pathogenicity of many bacteria, including <i>Streptococcus pneumoniae</i>, depends on pore-forming toxins (PFTs) that cause host cell lysis by forming large pores in cholesterol-containing cell membranes. Therefore, PFTs-neutralising antibodies may provide useful tools for reducing &...

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Bibliographic Details

Published in:	Biomolecules
Main Authors:	Indre Kucinskaite-Kodze, Martynas Simanavicius, Justas Dapkunas, Milda Pleckaityte, Aurelija Zvirbliene
Format:	Article
Language:	English
Published:	MDPI AG 2020-07-01
Subjects:	neutralising antibodies pneumolysin pore-forming toxins epitope mapping
Online Access:	https://www.mdpi.com/2218-273X/10/7/1009