Zika virus triggers autophagy to exploit host lipid metabolism and drive viral replication

Abstract Background Zika virus (ZIKV), an arbovirus of global concern, has been associated with neurological complications including microcephaly in newborns and Guillain–Barré syndrome in adults. Like other flaviviruses, ZIKV depends on cholesterol to facilitate its replication; thus, cholesterol h...

Full description

Bibliographic Details

Published in:	Cell Communication and Signaling
Main Authors:	Gloria Stoyanova, Sidra Jabeen, Joselyn Landazuri Vinueza, Sounak Ghosh Roy, Richard A. Lockshin, Zahra Zakeri
Format:	Article
Language:	English
Published:	BMC 2023-05-01
Subjects:	Zika virus Autophagy Lipid droplets Atorvastatin Statins Viral replication
Online Access:	https://doi.org/10.1186/s12964-022-01026-8