Reduced thyroxine production in young household contacts of tuberculosis patients increases active tuberculosis disease risk

In the current study, we followed 839 household contacts (HHCs) of tuberculosis (TB) patients for 2 years and identified the factors that enhanced the development of TB. Fourteen of the 17 HHCs who progressed to TB were in the 15- to 30-year-old age group. At baseline (the “0“ time point, when all t...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Kamakshi Prudhula Devalraju, Deepak Tripathi, Venkata Sanjeev Kumar Neela, Padmaja Paidipally, Rajesh Kumar Radhakrishnan, Karan P. Singh, Mohammad Soheb Ansari, Martin Jaeger, Romana T. Netea-Maier, Mihai G. Netea, Sunmi Park, Sheue-yann Cheng, Vijaya Lakshmi Valluri, Ramakrishna Vankayalapati
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2021-07-01
Subjects:	Immunology Pulmonology
Online Access:	https://doi.org/10.1172/jci.insight.148271