Affinity Chromatography‐Based Assays for the Screening of Potential Ligands Selective for G‐Quadruplex Structures

Abstract DNA G‐quadruplexes (G4s) are key structures for the development of targeted anticancer therapies. In this context, ligands selectively interacting with G4s can represent valuable anticancer drugs. Aiming at speeding up the identification of G4‐targeting synthetic or natural compounds, we de...

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Bibliographic Details
Published in:ChemistryOpen
Main Authors: Dr. Chiara Platella, Dr. Ettore Napolitano, Dr. Claudia Riccardi, Prof. Domenica Musumeci, Prof. Daniela Montesarchio
Format: Article
Language:English
Published: Wiley-VCH 2022-05-01
Subjects:
affinity chromatography
cancer
drug discovery
G-quadruplexes
oligonucleotides
Online Access:https://doi.org/10.1002/open.202200090

Internet

https://doi.org/10.1002/open.202200090

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