An amphiregulin reporter mouse enables transcriptional and clonal expansion analysis of reparative lung Tregs

Regulatory T cells (Tregs) are known to play critical roles in tissue repair via provision of growth factors, such as amphiregulin (Areg). Areg-producing Tregs have previously been difficult to study because of an inability to isolate live Areg-producing cells. In this report, we created a reporter...

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Bibliographic Details

Published in:	JCI Insight
Main Authors:	Lucas F. Loffredo, Katherine A. Kaiser, Adam Kornberg, Samhita Rao, Kenia de los Santos-Alexis, Arnold Han, Nicholas Arpaia
Format:	Article
Language:	English
Published:	American Society for Clinical investigation 2025-07-01
Subjects:	Cell biology Immunology
Online Access:	https://doi.org/10.1172/jci.insight.187245