Holothurin A Inhibits RUNX1-Enhanced EMT in Metastasis Prostate Cancer via the Akt/JNK and P38 MAPK Signaling Pathway

Due to the challenge of prostate cancer (PCa) management, there has been a surge in efforts to identify more safe and effective compounds that can modulate the epithelial–mesenchymal transition (EMT) for driving metastasis. Holothurin A (HA), a triterpenoid saponin isolated from <i>Holothuria...

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Bibliographic Details

Published in:	Marine Drugs
Main Authors:	Sirorat Janta, Kanta Pranweerapaiboon, Pornpun Vivithanaporn, Anuchit Plubrukarn, Arthit Chairoungdua, Prachayaporn Prasertsuksri, Somjai Apisawetakan, Kulathida Chaithirayanon
Format:	Article
Language:	English
Published:	MDPI AG 2023-06-01
Subjects:	RUNX1 holothurin A EMT metastasis prostate cancer
Online Access:	https://www.mdpi.com/1660-3397/21/6/345