Thrombopoietin-independent generation of platelet-like particles from megakaryoblastic cells

Abstract The use of megakaryoblastic leukemia MEG-01 cells can help reveal the mechanisms of thrombopoiesis. However, conventional in vitro activation of platelet release from MEG-01 cells requires thrombopoietin, which is costly. Here, we aim to develop a more straightforward and affordable method....

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Nuntiporn Nunthanasup, Nutpakal Ketprasit, Egarit Noulsri, Attakorn Palasuwan, Valery Combes, Kasem Kulkeaw, Duangdao Palasuwan
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-12-01
Online Access:	https://doi.org/10.1038/s41598-023-50111-6