Hypertonic dextrose prolotherapy in osteoarthritis: mechanisms, efficacy, and future research directions

Osteoarthritis (OA) is a degenerative joint disease that causes pain, stiffness, and reduced mobility, significantly affecting the quality of life for millions globally. Current treatments focus on symptom management, with limited efficacy in addressing the underlying disease progression. Hypertonic...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Kai Huang, Haili Cai
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-08-01
Subjects:	osteoarthritis (OA) dextrose prolotherapy (DPT) hyaluronic acid (HA) platelet-rich plasma (PRP) physiotherapy
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2025.1602727/full