Leishmania amazonensis exhibits phosphatidylserine-dependent procoagulant activity, a process that is counteracted by sandfly saliva

Leishmania parasites expose phosphatidylserine (PS) on their surface, a process that has been associated with regulation of host's immune responses. In this study we demonstrate that PS exposure by metacyclic promastigotes of Leishmania amazonensis favours blood coagulation. L. amazonensis acce...

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Bibliographic Details

Published in:	Memorias do Instituto Oswaldo Cruz
Main Authors:	Natalia Cadaxo Rochael, Luize Goncalves Lima, Sandra Maria Pereira de Oliveira, Marcello Andre Barcinski, Elvira Maria Saraiva, Robson Queiroz Monteiro, Lucia Helena Pinto-da-Silva
Format:	Article
Language:	English
Published:	Fundação Oswaldo Cruz (FIOCRUZ) 2013-09-01
Subjects:	sandfly saliva Leishmania amazonensis phosphatidylserine blood coagulation Lutzomyia longipalpis
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000600679&lng=en&tlng=en