KrakenUniq: confident and fast metagenomics classification using unique k-mer counts

Abstract False-positive identifications are a significant problem in metagenomics classification. We present KrakenUniq, a novel metagenomics classifier that combines the fast k-mer-based classification of Kraken with an efficient algorithm for assessing the coverage of unique k-mers found in each s...

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Bibliographic Details

Published in:	Genome Biology
Main Authors:	F. P. Breitwieser, D. N. Baker, S. L. Salzberg
Format:	Article
Language:	English
Published:	BMC 2018-11-01
Subjects:	Metagenomics Microbiome Metagenomics classification Pathogen detection Infectious disease diagnosis
Online Access:	http://link.springer.com/article/10.1186/s13059-018-1568-0