Redox homeostasis modulation using theranostic AIE nanoparticles results in positive-feedback drug accumulation and enhanced drug penetration to combat drug-resistant cancer

Drug-resistant cancers usually have multiple barriers to compromise the effect of therapies, of which multidrug-resistance (MDR) phenotype as the intracellular barrier and dense tumor matrix as the extracellular barrier, significantly contribute to the poor anticancer performance of current drug del...

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Bibliographic Details

Published in:	Materials Today Bio
Main Authors:	Shaoqing Chen, Ziyu Wang, Li Liu, Yuting Li, Xinye Ni, Hong Yuan, Cheng Wang
Format:	Article
Language:	English
Published:	Elsevier 2022-12-01
Subjects:	Redox homeostasis modulation Multidrug drug resistance Drug delivery systems Positive-feedback Aggregation-induced emission
Online Access:	http://www.sciencedirect.com/science/article/pii/S2590006422001946