mRNA vaccine-induced IgG mediates nasal SARS-CoV-2 clearance in mice

Coronavirus disease 2019 (COVID-19) mRNA vaccines that have contributed to controlling the SARS-CoV-2 pandemic induce specific serum antibodies, which correlate with protection. However, the neutralizing capacity of antibodies for emerging SARS-CoV-2 variants is altered. Suboptimal antibody response...

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Bibliographic Details
Published in:Molecular Therapy: Nucleic Acids
Main Authors: Charlie Fricke, Lorenz Ulrich, Jana Kochmann, Janina Gergen, Kristina Kovacikova, Nicole Roth, Julius Beer, Daniel Schnepf, Thomas C. Mettenleiter, Susanne Rauch, Benjamin Petsch, Donata Hoffmann, Martin Beer, Björn Corleis, Anca Dorhoi
Format: Article
Language:English
Published: Elsevier 2024-12-01
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Online Access:http://www.sciencedirect.com/science/article/pii/S2162253124002476