Cell-Free Genic Extrachromosomal Circular DNA Profiles of DNase Knockouts Associated with Systemic Lupus Erythematosus and Relation with Common Fragile Sites

Cell-free extrachromosomal circular DNA (cf-eccDNA) has been proposed as a promising early biomarker for disease diagnosis, progression and drug response. Its established biomarker features are changes in the number and length distribution of cf-eccDNA. Another novel promising biomarker is a set of...

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Bibliographic Details

Published in:	Biomedicines
Main Authors:	Daniela Gerovska, Patricia Fernández Moreno, Aitor Zabala, Marcos J. Araúzo-Bravo
Format:	Article
Language:	English
Published:	MDPI AG 2023-12-01
Subjects:	extrachromosomal circular DNA (eccDNA) systemic lupus erythematosus (SLE) Dnase1 Dnase1l3 chromosomal fragile site (CFS) genome-wide association study (GWAS)
Online Access:	https://www.mdpi.com/2227-9059/12/1/80