Docosahexaenoic Acid Increases the Potency of Soluble Epoxide Hydrolase Inhibitor in Alleviating Streptozotocin-Induced Alzheimer’s Disease-Like Complications of Diabetes

Diabetes is a risk factor for Alzheimer’s disease and it is associated with significant memory loss. In the present study, we hypothesized that the soluble epoxide hydrolase (sEH) inhibitor N-[1-(1-oxopropyl)-4-piperidinyl]-N’-[4-(trifluoromethoxy)phenyl)-urea (also known as TPPU) could alleviate di...

وصف كامل

التفاصيل البيبلوغرافية

الحاوية / القاعدة:	Frontiers in Pharmacology
المؤلفون الرئيسيون:	Rohit Pardeshi, Nityanand Bolshette, Kundlik Gadhave, Mohammad Arfeen, Sahabuddin Ahmed, Rohitash Jamwal, Bruce D. Hammock, Mangala Lahkar, Sumanta Kumar Goswami
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	Frontiers Media S.A. 2019-04-01
الموضوعات:	Alzheimer’s disease-like complications of diabetes sEH inhibitor TPPU DHA Morris water maze novel object recognition test inflammatory cytokines
الوصول للمادة أونلاين:	https://www.frontiersin.org/article/10.3389/fphar.2019.00288/full