Small-Cell Carcinoma Transformation of Pulmonary Adenocarcinoma after Osimertinib Treatment: A Case Report

There are various mechanisms underlying the resistance of EGFR-mutant lung adenocarcinoma to epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs). We herein report a case of pulmonary adenocarcinoma with EGFR mutation (exon 19 deletion and T790M) that acquired resistance to osimer...

Full description

Bibliographic Details
Published in:Case Reports in Oncology
Main Authors: Yuri Taniguchi, Hajime Horiuchi, Teppei Morikawa, Kazuhiro Usui
Format: Article
Language:English
Published: Karger Publishers 2018-05-01
Subjects:
Osimertinib
T790M
Acquired resistance
Small-cell carcinoma transformation
Non-small-cell carcinoma
Epidermal growth factor receptor
Online Access:https://www.karger.com/Article/FullText/489603

Internet

https://www.karger.com/Article/FullText/489603

Similar Items