Biparental Inheritance and Instability of kDNA in Experimental Hybrids of <i>Trypanosoma cruzi</i>: A Proposal for a Mechanism

The mitochondrial DNA of trypanosomatid parasites consists of thousands of catenated minicircles and dozens of maxicircles that form a complex network structure, the kinetoplast (kDNA). Although kDNA replication and segregation during mitotic division are well studied, its inheritance during genetic...

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Bibliographic Details

Published in:	Biology
Main Authors:	Nicolás Tomasini, Tatiana Ponce, Fanny Rusman, Soledad Hodi, Noelia Floridia-Yapur, Anahí Guadalupe Díaz, Juan José Aguirre, Gabriel Machado Matos, Björn Andersson, Michael D. Lewis, Patricio Diosque
Format:	Article
Language:	English
Published:	MDPI AG 2025-10-01
Subjects:	<i>Trypanosoma cruzi</i> laboratory hybrid kDNA inheritance minicircle maxicircle Replicative MIXing (REMIX) model
Online Access:	https://www.mdpi.com/2079-7737/14/10/1394