Identification of critical residues at the C-terminal tip of ACKR4 regulating chemokine internalization and βarrestin involvement

Abstract Background Atypical chemokine receptors (ACKRs) play an important role in regulating the availability of chemokines and are responsible for the formation of chemokine gradients required for the directed migration of immune cells in health and disease. ACKR4 shapes gradients of the chemokine...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Cell Communication and Signaling
المؤلفون الرئيسيون: Oliver J. Gerken, Nicola Catone, Daniel F. Legler
التنسيق: مقال
اللغة:الإنجليزية
منشور في: BMC 2024-12-01
الموضوعات:
Chemokine
ACKR4
CCL19
Receptor tagging
βarrestin
PDZ proteins
الوصول للمادة أونلاين:https://doi.org/10.1186/s12964-024-01961-8

الانترنت

https://doi.org/10.1186/s12964-024-01961-8

مواد مشابهة