Metabolomics and Network Analyses Reveal Phenylalanine and Tyrosine as Signatures of Anthracycline-Induced Hepatotoxicity

The chemotherapy drug doxorubicin (DOX) is an anthracycline with over 30% incidence of liver injury in breast cancer patients, yet the mechanism of its hepatotoxicity remains unclear. To identify potential biomarkers for anthracycline-induced hepatotoxicity (AIH), we generated clinically-relevant mo...

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Bibliographic Details
Published in:Pharmaceuticals
Main Authors: Peipei Liu, Jing Wu, Xinyue Yu, Linling Guo, Ling Zhao, Tao Ban, Yin Huang
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Subjects:
hepatotoxicity
chemotherapy
metabolomics
network
Online Access:https://www.mdpi.com/1424-8247/16/6/797

Internet

https://www.mdpi.com/1424-8247/16/6/797

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