Cellular parameters shaping pathways of targeted protein degradation

Abstract In recent years the development of proteolysis-targeting chimeras (PROTACs) has enhanced the field of ubiquitin signalling through advancing therapeutic targeted protein degradation (TPD) strategies and generating tools to explore the ubiquitin landscape. However, the interplay between PROT...

詳細記述

書誌詳細
出版年:Communications Biology
主要な著者: Annabel Cardno, Bryony Kennedy, Catherine Lindon
フォーマット: 論文
言語:英語
出版事項: Nature Portfolio 2025-05-01
オンライン・アクセス:https://doi.org/10.1038/s42003-025-08104-w